CHEMBL549638


SMILES Cc1cc2nc(C)c(CN3CCN(c4ccc(F)cc4)CC3)n2c(C)n1
InChIKey RTYGYVMXTLAVMS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.92 4.92 4.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.66 4.66 4.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.33 5.39 5.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.33 5.39 5.46 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database