EXISULIND


SMILES CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc(S(C)(=O)=O)cc1
InChIKey MVGSNCBCUWPVDA-MFOYZWKCSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 372.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETA EDNRA Human Endothelin A pKi 5.22 5.22 5.22 ChEMBL
ETA EDNRA Human Endothelin A pKi 8.28 8.28 8.28 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.05 7.05 7.05 ChEMBL
ETA EDNRA Human Endothelin A pIC50 5.01 5.01 5.01 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.4 5.4 5.4 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.8 4.8 4.8 ChEMBL