CHEMBL561262


SMILES COc1ccccc1N1CCN(Cc2c(C)nc3cc(C)ncn23)CC1
InChIKey KOFYUIUZURNMRL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.23 4.23 4.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.17 4.17 4.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.28 4.34 4.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database