CHEMBL5315342


SMILES COCCCC(=O)N(C)CCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O
InChIKey AMOACTSTZUXXDX-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 11
Molecular weight (Da) 510.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
H1 HRH1 Human Histamine A pKi 8.5 8.5 8.5 ChEMBL
H1 HRH1 Human Histamine A pKd 10.0 10.0 10.0 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database