CHEMBL563109


SMILES COc1ccccc1N1CCN(Cc2cnc3cc(C)nc(C)n23)CC1
InChIKey VGIPYYQGXWSQEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.96 4.96 4.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.89 6.06 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.89 6.06 6.24 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.82 5.82 5.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database