(R)-DOI


SMILES COc1cc(I)c(cc1C[C@H](N)C)OC
InChIKey BGMZUEKZENQUJY-SSDOTTSWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 321.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.2 9.22 9.3 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.3 7.53 7.4 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.4 8.23 8.7 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pEC50 7.92 7.92 7.92 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 7.52 7.52 7.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.42 5.42 5.42 ChEMBL