CHEMBL510437


SMILES Cc1ccc([C@H](Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)C)o1
InChIKey UNPQYPMTWSIZRR-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pKi 7.82 7.82 7.82 ChEMBL
CXCR2 CXCR2 Human Chemokine A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pIC50 5.41 5.41 5.41 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 7.44 7.44 7.44 ChEMBL