CHEMBL56118
SMILES | N#Cc1c[nH]c(CN2CCN(c3ccccc3)CC2)c1 |
InChIKey | IKBANCXZZJPIEB-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 266.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 6.21 | 6.21 | 6.21 | ChEMBL |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.34 | 5.34 | 5.34 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.68 | 7.68 | 7.68 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.75 | 5.75 | 5.75 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.35 | 6.35 | 6.35 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.1 | 5.26 | 5.43 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pEC50 | 8.25 | 8.25 | 8.25 | ChEMBL |