CHEMBL572379


SMILES O=C(CCCc1cn(-c2ccc([N+](=O)[O-])cc2)nn1)NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey LFQLOBUDZGJGBE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 559.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.75 6.75 6.75 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.55 7.55 7.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.28 7.32 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database