GPCRdb

CHEMBL5420881

Agent/drug
Bioactivity

CHEMBL5420881

SMILES	Cc1ccccc1OCC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O
InChIKey	HDESYZHTQAEDLX-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	369.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

Y₄	NPY4R	Human	Neuropeptide Y	A	pKi	8.36	8.36	8.36	ChEMBL
Y₄	NPY4R	Human	Neuropeptide Y	A	pKd	7.51	7.51	7.51	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

Y₁	NPY1R	Human	Neuropeptide Y	A	pEC50	10.32	10.32	10.32	ChEMBL
Y₂	NPY2R	Human	Neuropeptide Y	A	pEC50	10.79	10.79	10.79	ChEMBL
Y₄	NPY4R	Rat	Neuropeptide Y	A	pEC50	9.51	9.51	9.51	ChEMBL
Y₄	NPY4R	Mouse	Neuropeptide Y	A	pEC50	10.15	10.15	10.15	ChEMBL
Y₄	NPY4R	Human	Neuropeptide Y	A	pEC50	6.90	8.10	10.51	ChEMBL
Y₅	NPY5R	Human	Neuropeptide Y	A	pEC50	8.73	8.73	8.73	ChEMBL

Showing 1 to 6 of 6 entries

CHEMBL5420881

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.