CHEMBL514606


SMILES CCCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O
InChIKey VFEHYWWZSNCIAC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 453.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.24 7.24 7.24 ChEMBL
δ OPRD Human Opioid A pKi 4.23 4.23 4.23 ChEMBL
κ OPRK Human Opioid A pKi 6.11 6.11 6.11 ChEMBL
μ OPRM Human Opioid A pKi 5.07 5.07 5.07 ChEMBL
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
NOP OPRX Human Opioid A pKi 7.24 7.24 7.24 PDSP Ki database
κ OPRK Human Opioid A pKi 6.11 6.11 6.11 PDSP Ki database
μ OPRM Human Opioid A pKi 5.07 5.07 5.07 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database