CHEMBL515575


SMILES CC(C)CCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey XMLGFWNLDRPFTA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 502.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.4 9.4 9.4 ChEMBL
δ OPRD Human Opioid A pKi 5.58 5.58 5.58 ChEMBL
κ OPRK Human Opioid A pKi 7.09 7.09 7.09 ChEMBL
μ OPRM Human Opioid A pKi 6.69 6.69 6.69 ChEMBL
NOP OPRX Human Opioid A pKi 9.4 9.4 9.4 PDSP Ki database
δ OPRD Human Opioid A pKi 5.59 5.59 5.59 PDSP Ki database
κ OPRK Human Opioid A pKi 7.09 7.09 7.09 PDSP Ki database
μ OPRM Human Opioid A pKi 6.69 6.69 6.69 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database