Chembl69678

Chemical Properties

SMILES Nc1cccc(CN2CCC(NC(=O)[C@](O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)n1
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight 444.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey HQRSMNLSFMUJPL-KOSHJBKYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.55 8.55 8.55 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.28 6.28 6.28 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.82 8.82 8.82 ChEMBL