CHEMBL574827


SMILES O=c1c2ccccc2ncn1CCCCN1CCN(c2cccc(Cl)c2)CC1
InChIKey XGTCJFHULKEJKG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.3 7.79 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database