Ligand Data
Ligand
| Name | JMV431 |
| SMILES | None |
| InChIKey | DQDBCHHEIKQPJD-ODKJCKIQSA-N |
| Type | peptide |
| Sequence | RRPYIL |
| External Links | |
| Structure pdb | 4GRV 6UP7 6YVR 6Z4V |
Structure
Properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| NTS1 | NTR1 | Rat | Neurotensin | A (Rhodopsin) | 1.3 | 1.3 | 1.3 | |||
| NTS2 | NTR2 | Human | Neurotensin | A (Rhodopsin) | 0.6 | 3.0 | 7.5 | |||
| NTS1 | NTR1 | Human | Neurotensin | A (Rhodopsin) | 0.1 | 0.6 | 1.3 | 0.0 | 0.8 | 1.9 |