CHEMBL607405


SMILES CO[C@@]12CCC(=O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5
InChIKey FCIDDJPMOSRHJG-XFKAJCMBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 315.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 5.58 7.19 7.99 ChEMBL
μ OPRM Rat Opioid A pKi 7.36 9.12 10.0 ChEMBL
δ OPRD Human Opioid A pKi 8.06 8.06 8.06 ChEMBL
κ OPRK Human Opioid A pKi 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pKi 9.49 9.49 9.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 7.52 7.52 7.52 ChEMBL
δ OPRD Human Opioid A pEC50 7.43 7.43 7.43 ChEMBL
κ OPRK Human Opioid A pEC50 6.94 6.94 6.94 ChEMBL
μ OPRM Human Opioid A pEC50 8.42 8.63 8.84 ChEMBL