CHEMBL5288557
SMILES | O=C(Cn1c(CCCN2CCN(c3cccc(Cl)c3Cl)CC2)nc2ccccc21)NCc1ccccc1 |
InChIKey | RCOOYZUDBHDXOZ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 9 |
Molecular weight (Da) | 535.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pIC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 4.42 | 4.42 | 4.42 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 4.87 | 4.87 | 4.87 | ChEMBL |