CHEMBL64553


SMILES Oc1ccc2c(c1)O[C@@H](CNCc1ccccc1)CC2
InChIKey DWUAAOIZQFTYQP-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.42 5.42 5.43 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.14 5.17 5.21 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.94 7.33 7.93 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.48 9.17 9.8 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.65 7.65 7.65 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.5 8.58 8.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.13 7.64 8.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 10.7 10.7 10.7 ChEMBL