CHEMBL64566


SMILES COc1ccc(Br)cc1-c1nc(CNC[C@@H]2CCN(Cc3ccccc3)C2)c[nH]1
InChIKey XWPFAYFZWMVJSL-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 454.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.05 5.05 5.05 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.2 5.38 5.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database