CHEMBL60583


SMILES CC(C)Oc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
InChIKey WOTQTCOGYGHNIU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 413.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.3 8.3 8.3 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 8.45 8.45 8.45 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.55 8.55 8.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.27 9.27 9.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database