CHEMBL556313


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc(F)ccc2F)CC1
InChIKey NWSVOKGXCYCZTI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.85 9.85 9.85 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.27 7.75 8.23 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.87 6.87 6.87 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.02 9.02 9.02 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.21 7.4 7.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database