NAXAGOLIDE


SMILES CCCN1CCO[C@@H]2c3cc(O)ccc3CC[C@H]21
InChIKey JCSREICEMHWFAY-HUUCEWRRSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 247.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 9.22 9.22 9.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.97 9.43 9.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.67 8.3 9.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 8.52 8.52 8.52 ChEMBL