GPCRdb

THIOPROPERAZINE

Agent/drug
Bioactivity

THIOPROPERAZINE

SMILES	CN1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1
InChIKey	VZYCZNZBPPHOFY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	446.2

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

THIOPROPERAZINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Schizophrenia or other primary psychotic disorders, unspecified	6A2Z		0.370	4	Yes
ADA1A	α_1A-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Schizophrenia, episode unspecified	6A20.Z		0.565	4	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Schizophrenia or other primary psychotic disorders, unspecified	6A2Z		0.370	4	Yes
ADA1B	α_1B-adrenoceptor	Adrenoceptors	Aminergic receptors	Class A	Schizophrenia, episode unspecified	6A20.Z		0.561	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Bipolar type I disorder, unspecified	6A60.Z		0.660	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Nausea or vomiting	MD90		0.573	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Schizophrenia or other primary psychotic disorders, unspecified	6A2Z		0.615	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Schizophrenia, episode unspecified	6A20.Z		0.732	4	Yes

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