seglitide
| SMILES | None |
| InChIKey | NPJIOCBFOAHEDO-AVWFULIKSA-N |
| Sequence | AYWKVF |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H3 | HRH3 | Human | Histamine | A | pKi | 7.6 | 7.6 | 7.6 | Guide to Pharmacology |
| H3 | HRH3 | Rat | Histamine | A | pKi | 6.6 | 6.6 | 6.6 | Guide to Pharmacology |
| H4 | HRH4 | Human | Histamine | A | pKi | 5.4 | 5.4 | 5.4 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pKi | 5.79 | 6.46 | 7.2 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pKi | 5.5 | 5.5 | 5.5 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H4 | HRH4 | Human | Histamine | A | pEC50 | 4.9 | 4.9 | 4.9 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pEC50 | 8.0 | 8.0 | 8.0 | ChEMBL |