Chembl3580744


SMILES NC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(C(F)(F)F)cc2)C(=O)N1
InChIKey RJZXRAGFTZLOMH-JZVHMONDSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pIC50 6.37 6.37 6.37 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 8.82 8.82 8.82 ChEMBL
μ OPRM Rat Opioid A pIC50 8.8 8.8 8.8 ChEMBL
δ OPRD Human Opioid A pEC50 6.79 6.79 6.79 ChEMBL
κ OPRK Human Opioid A pEC50 7.93 7.93 7.93 ChEMBL
μ OPRM Human Opioid A pEC50 8.28 8.28 8.28 ChEMBL