GPCRdb

ITRACONAZOLE

Agent/drug
Bioactivity

ITRACONAZOLE

SMILES	CCC(C)n1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(Cn6cncn6)(c6ccc(Cl)cc6Cl)O5)cc4)CC3)cc2)c1=O
InChIKey	VHVPQPYKVGDNFY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	12
Hydrogen bond donors	0
Rotatable bonds	11
Molecular weight (Da)	704.2

Database connections

ChEMBL_compound_ids PubChem PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₂	ADRB2	Human	Adrenoceptors	A	pKi	8.20	8.20	8.20	Drug Central

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCR4	CCR4	Human	Chemokine	A	pIC50	4.90	5.63	6.70	ChEMBL
CCR4	CCR4	Human	Chemokine	A	pIC50	8.17	8.17	8.17	Drug Central
CXCR1	CXCR1	Human	Chemokine	A	pIC50	4.68	5.63	7.00	ChEMBL
CXCR1	CXCR1	Human	Chemokine	A	pIC50	8.15	8.15	8.15	Drug Central
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	4.90	5.41	6.10	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	8.21	8.21	8.21	Drug Central

Showing 1 to 6 of 6 entries

ITRACONAZOLE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem PubChem GPCRdb

Compound is not listed as a drug.