CHEMBL83915


SMILES COc1cc2c(cc1OC)C(CCN1CCN(c3ccc(F)cc3)CC1)OCC2
InChIKey PAHAVOZGHBZJNZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.62 7.62 7.62 ChEMBL
D1 DRD1 Rat Dopamine A pKi 7.58 7.58 7.58 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database