GPCRdb

ETHINYL ESTRADIOL

Agent/drug
Bioactivity

ETHINYL ESTRADIOL

SMILES	C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C
InChIKey	BFPYWIDHMRZLRN-SLHNCBLASA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	0
Molecular weight (Da)	296.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pKi	4.99	4.99	4.99	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.30	8.30	8.30	Drug Central
μ	OPRM	Human	Opioid	A	pKi	4.96	4.96	4.96	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.30	8.30	8.30	Drug Central
5-HT₄	5HT4R	Guinea pig	5-Hydroxytryptamine	A	pKi	8.23	8.23	8.23	Drug Central
A_2A	AA2AR	Human	Adenosine	A	pKi	4.93	4.93	4.93	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	8.31	8.31	8.31	Drug Central
A₃	AA3R	Human	Adenosine	A	pKi	4.73	4.73	4.73	ChEMBL
A₃	AA3R	Human	Adenosine	A	pKi	8.33	8.33	8.33	Drug Central

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pIC50	4.59	4.59	4.59	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	4.57	4.57	4.57	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pIC50	4.68	4.68	4.68	ChEMBL
A₃	AA3R	Human	Adenosine	A	pIC50	4.48	4.48	4.48	ChEMBL

Showing 1 to 4 of 4 entries

ETHINYL ESTRADIOL

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.