CHEMBL93868


SMILES CN(C)CCc1cn(S(=O)(=O)c2ccccc2)c2ccccc12
InChIKey NKLZWGMWROXIDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 328.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.39 8.47 8.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database