CHEMBL60185


SMILES c1ccc(CNC[C@H]2CCc3ccc4[nH]ccc4c3O2)cc1
InChIKey AERWLNZHDGJKMO-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 292.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.45 8.09 8.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.47 7.47 7.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database