CHEMBL235743


SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey RJEUERNNQHNSKG-CCKFTAQKSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.76 6.76 6.76 ChEMBL
μ OPRM Rat Opioid A pKi 8.55 8.66 9.1 ChEMBL
δ OPRD Human Opioid A pKi 6.52 6.52 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 6.92 6.92 6.92 ChEMBL
μ OPRM Rat Opioid A pEC50 6.81 7.71 7.98 ChEMBL
μ OPRM Rat Opioid A pIC50 8.2 8.23 8.24 ChEMBL
δ OPRD Human Opioid A pEC50 6.72 6.72 6.72 ChEMBL
δ OPRD Human Opioid A pIC50 6.1 6.13 6.14 ChEMBL
κ OPRK Human Opioid A pIC50 6.65 6.65 6.65 ChEMBL