CHEMBL605831


SMILES Cn1c(CN2CCC(c3nc4ccccc4s3)CC2)nc2ccccc21
InChIKey ZDOBRSDAKYWSHM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.1 8.1 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.5 6.15 6.8 ChEMBL