NIFLUMIC ACID
SMILES | O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1 |
InChIKey | JZFPYUNJRRFVQU-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 3 |
Molecular weight (Da) | 282.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR35 | GPR35 | Human | A orphans | A | pKi | 5.44 | 5.44 | 5.44 | ChEMBL |
GPR35 | GPR35 | Human | A orphans | A | pKi | 8.26 | 8.26 | 8.26 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR35 | GPR35 | Human | A orphans | A | pEC50 | 4.4 | 5.13 | 5.96 | ChEMBL |
GPR35 | GPR35 | Human | A orphans | A | pIC50 | 5.89 | 5.89 | 5.89 | ChEMBL |