MEDETOMIDINE


SMILES Cc1cccc(C(C)c2c[nH]cn2)c1C
InChIKey CUHVIMMYOGQXCV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 200.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.5 6.5 6.5 PDSP Ki database
α2A ADA2A Human Adrenoceptors A pKi 7.8 8.22 8.69 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 7.47 7.96 8.7 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 7.02 7.81 8.6 PDSP Ki database
α1D ADA1D Rat Adrenoceptors A pKi 7.2 7.2 7.2 PDSP Ki database
α1B ADA1B Rat Adrenoceptors A pKi 6.5 6.5 6.5 PDSP Ki database
α2A ADA2A Mouse Adrenoceptors A pKi 8.47 8.47 8.47 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 6.7 6.9 7.1 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pIC50 5.47 5.47 5.47 ChEMBL