nepadutant
SMILES | None |
InChIKey | NPSVXOVMLVOMDD-SXRVEDALSA-N |
Sequence | NDWFXL |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pKi | 8.1 | 8.1 | 8.1 | Guide to Pharmacology |
δ | OPRD | Human | Opioid | A | pKi | 5.06 | 5.06 | 5.06 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 5.98 | 5.98 | 5.98 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 6.99 | 6.99 | 6.99 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 8.09 | 8.09 | 8.09 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Human | Opioid | A | pIC50 | 5.12 | 5.12 | 5.12 | ChEMBL |
μ | OPRM | Human | Opioid | A | pIC50 | 5.82 | 5.82 | 5.82 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pIC50 | 7.52 | 7.52 | 7.52 | ChEMBL |