LY-389795


SMILES N[C@@]1(C(=O)O)CS[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey QBHIOYZCUZBIEN-MDASVERJSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 203.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.77 7.87 8.33 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.09 7.01 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pEC50 5.13 5.13 5.13 ChEMBL
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 5.61 5.61 5.61 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 8.12 8.12 8.12 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 8.41 8.41 8.41 ChEMBL