CHEMBL92139


SMILES CN(C)CCc1cccc2c1ccn2S(=O)(=O)c1ccccc1
InChIKey GIHFRARKMBMXPG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 328.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.41 8.41 8.41 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.82 8.82 8.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database