PHENYLPIPERAZINE


SMILES c1ccc(N2CCNCC2)cc1
InChIKey YZTJYBJCZXZGCT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 162.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKi 5.87 5.87 5.87 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.17 5.17 5.17 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.82 6.36 6.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pIC50 4.72 4.72 4.72 ChEMBL