CARBACHOL
SMILES | C[N+](C)(C)CCOC(=O)N.[Cl-] |
InChIKey | AIXAANGOTKPUOY-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 182.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 5.0 | 6.9 | 8.89 | PDSP Ki database |
M2 | ACM2 | Rat | Acetylcholine (muscarinic) | A | pKi | 5.35 | 5.59 | 5.7 | PDSP Ki database |
M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pKi | 7.2 | 7.55 | 7.92 | PDSP Ki database |
M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pKi | 5.81 | 6.96 | 8.12 | PDSP Ki database |
M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pKi | 5.0 | 6.66 | 7.7 | PDSP Ki database |
M3 | ACM3 | Rat | Acetylcholine (muscarinic) | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pKi | 8.37 | 8.37 | 8.37 | PDSP Ki database |
M1 | ACM1 | Mouse | Acetylcholine (muscarinic) | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
M2 | ACM2 | Mouse | Acetylcholine (muscarinic) | A | pKi | 8.09 | 8.09 | 8.09 | Drug Central |
M2 | ACM2 | Rat | Acetylcholine (muscarinic) | A | pKi | 8.08 | 8.08 | 8.08 | Drug Central |
M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | pKi | 8.12 | 8.12 | 8.12 | Drug Central |
M4 | ACM4 | Rat | Acetylcholine (muscarinic) | A | pKi | 8.25 | 8.25 | 8.25 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.07 | 8.07 | 8.07 | Drug Central |
M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.1 | 8.1 | 8.1 | Drug Central |
M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.06 | 8.06 | 8.06 | Drug Central |
M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.12 | 8.12 | 8.12 | Drug Central |
M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.09 | 8.09 | 8.09 | Drug Central |