Leuprolide


SMILES None
InChIKey GFIJNRVAKGFPGQ-LIJARHBVSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKi 8.5 8.8 9.1 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 9.1 9.1 9.1 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 9.1 9.23 9.3 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 9.1 9.42 9.54 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.02 7.02 7.02 Drug Central
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 7.03 7.03 7.03 Drug Central