TENILAPINE


SMILES CN1CCN(CC1)C2=NC3=CSC=C3C(=CC#N)C4=CSC=C42
InChIKey RVQVUMIXBGFJLZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 340.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 PDSP Ki database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.2 7.21 7.21 PDSP Ki database
D4 DRD4 Rat Dopamine A pKi 6.14 6.14 6.14 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 5.8 5.8 5.8 PDSP Ki database
5-HT6 5HT6R Rat 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.28 6.28 6.28 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.59 6.59 6.59 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.21 7.21 7.21 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.18 6.18 6.18 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.37 6.37 6.37 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database