2-(2-chlorophenyl)-1-(4-chlorophenyl)-N-((1R,2R)-2-hydroxycyclohexyl)-1H-imidazole-4-carboxamide


SMILES C1CCC(C(C1)NC(=O)C2=CN(C(=N2)C3=CC=CC=C3Cl)C4=CC=C(C=C4)Cl)O
InChIKey YANPAVHFFWLLEL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 7.01 7.28 7.54 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.28 5.28 5.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database