JWH-018


SMILES CCCCCn1cc(c2c1cccc2)C(=O)c1cccc2c1cccc2
InChIKey JDNLPKCAXICMBW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Mouse Cannabinoid A pKi 8.89 8.89 8.89 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 8.02 8.31 8.54 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 8.02 8.39 8.7 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 8.0 8.0 8.0 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pKi 8.5 8.5 8.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 7.66 7.98 8.3 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 7.45 7.74 8.3 ChEMBL