GPCRdb

SULPIRIDE,(-)

SMILES	CCN1CCCC1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC
InChIKey	BGRJTUBHPOOWDU-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	341.1

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

SULPIRIDE,(-)

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 3

Phase IV 19

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Anxiety	4	MB24.3		0.272
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Bipolar type I disorder, unspecified	4	6A60.Z		0.078
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Depressive disorders, unspecified	3	6A7Z		0.404
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Gastro-oesophageal reflux disease, unspecified	4	DA22.Z		0.536
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Irritable bowel syndrome, type unspecified	4	DD91.0Z		0.538
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Schizophrenia, episode unspecified	4	6A20.Z		0.609
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Single episode depressive disorder, severe, without psychotic symptoms	4	6A70.3		0.060
5HT4R	5-HT₄ receptor	5-Hydroxytryptamine receptors	Aminergic receptors	A	Vertigo, unspecified	4	MB48.0Z		0.370
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Anxiety	4	MB24.3		0.578
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Bipolar type I disorder, unspecified	4	6A60.Z		0.660
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Depressive disorders, unspecified	3	6A7Z		0.655
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Gastro-oesophageal reflux disease, unspecified	4	DA22.Z		0.558
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Hallucinations, unspecified	4	MB27.2Z		0.074
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Irritable bowel syndrome, type unspecified	4	DD91.0Z		0.074
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Schizophrenia, episode unspecified	4	6A20.Z		0.732
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Single episode depressive disorder, severe, without psychotic symptoms	4	6A70.3		0.703
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	A	Vertigo, unspecified	4	MB48.0Z		0.370

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SULPIRIDE,(-)

SULPIRIDE,(-)

Chemical Properties

Database connections

No bioactivity data available.

SULPIRIDE,(-)

Drug properties

Distribution across phases (no. indications)

Database connections

Sankey plot

Drug Information