mozavaptan


SMILES O=C(N1CCCC(c2c1cccc2)N(C)C)c1ccc(cc1)NC(=O)c1ccccc1C
InChIKey WRNXUQJJCIZICJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Rat Vasopressin and oxytocin A pKi 6.96 6.96 6.96 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 6.7 6.7 6.7 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pKi 8.44 8.44 8.44 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 6.23 6.23 6.23 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 6.75 6.75 6.75 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 7.89 7.89 7.89 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.1 8.1 8.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Rat Vasopressin and oxytocin A pIC50 6.43 6.43 6.43 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pIC50 6.24 6.24 6.24 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pIC50 8.05 8.05 8.05 ChEMBL