SSR126768A


SMILES CCN(C(=O)c1ccc(c(c1)[C@@]1(C)c2cc(Cl)ccc2N(C1=O)Cc1ccc(cc1OC)OC)Cl)Cc1cccnc1
InChIKey UENRBNCNIZQNTR-XIFFEERXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 603.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Human Vasopressin and oxytocin A pKi 8.4 8.4 8.4 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 9.12 9.12 9.12 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 5.01 5.01 5.01 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pKi 7.82 7.83 7.85 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 4.55 4.55 4.55 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.31 8.35 8.39 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database