CHEMBL1221498


SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1
InChIKey VUQFQRNHGGYQGK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.77 8.77 8.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.63 8.63 8.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database