CHEMBL1223749


SMILES Clc1cccc(N2CCN(CCCCNc3nccc4ccccc34)CC2)c1Cl
InChIKey DPAGUJADGMJVKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.22 7.22 7.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.51 8.51 8.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.72 8.12 8.51 ChEMBL
H4 HRH4 Human Histamine A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database