levocabastine


SMILES N#C[C@@]1(CC[C@@H](CC1)N1CC[C@]([C@@H](C1)C)(C(=O)O)c1ccccc1)c1ccc(cc1)F
InChIKey ZCGOMHNNNFPNMX-KYTRFIICSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 8.14 8.14 8.14 Drug Central
NTS2 NTR2 Human Neurotensin A pKi 8.17 8.17 8.17 Drug Central
NTS2 NTR2 Human Neurotensin A pKi 6.8 6.8 6.8 Guide to Pharmacology
NTS2 NTR2 Rat Neurotensin A pKi 8.13 8.13 8.13 Drug Central
NTS2 NTR2 Rat Neurotensin A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NTS2 NTR2 Rat Neurotensin A pEC50 7.55 7.55 7.55 ChEMBL
NTS2 NTR2 Rat Neurotensin A pIC50 8.0 8.0 8.0 Guide to Pharmacology
NTS2 Q920Q5 Mouse Neurotensin A pIC50 8.4 8.55 8.7 Guide to Pharmacology