Ml321


SMILES O=C(c1ccc2c(c1)N(C)C(=O)c1c([S@@]2=O)cccc1)NCCc1cccs1
InChIKey YXLLQNMKIDBOGH-NDEPHWFRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 410.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.0 7.0 7.0 Guide to Pharmacology
D3 DRD3 Human Dopamine A pAC50 4.89 4.89 4.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.39 5.39 5.39 ChEMBL
D2 DRD2 Human Dopamine A pAC50 6.14 6.65 7.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL